SGTB

small glutamine rich tetratricopeptide repeat co-chaperone beta

Ensembl:
ENSG00000197860
UniProt:
Q96EQ0
OMIM:
620526
Synonyms:
FLJ39002, SGT2

Cilia effects upon perturbation of SGTB

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-7.64) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse ciliopathy phenotype:
abnormal uterus morphology

Subcellular localization

cilia

Functional category

  • Ciliary assembly/disassembly
  • Protein processing & maturation

Function

SGTB has localized in primary cilia.