?

Phenotypes

Mouse phenotype:

decreased circulating calcium level

Subcellular localization

cilia, Nucleoplasm, Plasma membrane

Function

We also confirmed ciliary localizations for SYNGAP1, STXBP1, PSD95, SCN2A, SLC6A1, and SHANK3 by antibody staining in rat brain cells (Fig. 3C, S8C, S9A). Together, these results suggest that autism proteins with annotated functions in neuronal communication also localize to cilia and therefore may share a previously unrecognized common function at this structure(39677731).