SLC30A7

solute carrier family 30 member 7

Ensembl:
ENSG00000162695
UniProt:
Q8NEW0
OMIM:
611149
Synonyms:
ZNT7, ZNTL2

Cilia effects upon perturbation of SLC30A7

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-13.36) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:
impaired glucose tolerance, increased cornea thickness, thin ventricular wall, decreased lean body mass, increased total body fat amount
Mouse ciliopathy phenotype:
female infertility, male infertility

Subcellular localization

cilia associated gene

Functional category

  • Ciliary assembly/disassembly

Function

SLC30A7 is a candidate JS-associated gene ( 35751429).