SLC6A12

solute carrier family 6 member 12

Tier: Cilia-Associated Genes

Ensembl:
ENSG00000111181
UniProt:
P48065
OMIM:
603080
Synonyms:
BGT-1

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

No ciliary localization reported (cilia-associated gene).

References: PMID:28122715

Functional category

  • Ciliary assembly/disassembly

Function

Hyperosmolal stress induced Akr1b3 and Slc6a12 expression in both cell lines, but the response was greater in ciliated than nonciliated cells ( 28122715).