SLC9B2

solute carrier family 9 member B2

Ensembl:
ENSG00000164038
UniProt:
Q86UD5
OMIM:
611789
Synonyms:
FLJ23984, NHA2, NHEDC2

Cilia effects upon perturbation of SLC9B2

Ciliogenesis screen results (2 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Phenotypes

Mouse phenotype:
increased circulating phosphate level

Subcellular localization

flagella

Functional category

  • Actin & cytoskeleton regulation
  • T cell biology
  • Reproduction & sperm
  • Cell migration & adhesion
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

NHA2 is specifically localized in the principal piece of sperm tail, which is similar to NHA1 expression pattern (27010853).