SLCO6A1

solute carrier organic anion transporter family member 6A1

Ensembl:
ENSG00000205359
UniProt:
Q86UG4
OMIM:
613365
Synonyms:
CT48, MGC26949, OATP6A1, OATPY

Cilia effects upon perturbation of SLCO6A1

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-3.79) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

flagella

Functional category

  • Metabolism

Function

As the wing structure is seen in the mouse but not human CatSper , the association of SLCO6C1 with CatSper channel complex might be a species-specific molecular mechanism such as linking Ca2+ homeostasis to ATP production (35715406).