SMC5

structural maintenance of chromosomes 5

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000198887
UniProt:: Q8IY18
OMIM:: 609386
Synonyms:: SMC5L1, KIAA0594

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: Increased Signaling (Negative Regulator) PMID:29459680

Subcellular localization

cilia, nuclear speckles

References: PMID:41410385

Function

SMC5 has located to motile cilia.

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