SPATA4

spermatogenesis associated 4

Ensembl:: ENSG00000150628
UniProt:: Q8NEY3
OMIM:: 609879
Synonyms:: CFAP178, FAP178, SPEF1B, TSARG2

Cilia effects upon perturbation of SPATA4

Cilia number / % ciliated:: Decreased cilia number
Loss-of-function effect:: No effect

Ciliogenesis screen results (3 screens)

Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-4.25) PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

cilia associated gene

Functional category

Ciliary assembly/disassembly
Actin & cytoskeleton regulation
Reproduction & sperm

Function

Knockdown of SPATA4 causes few cells to build a cilium ( 23604077).

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