SRA1

steroid receptor RNA activator 1

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000213523
UniProt:
Q9HD15
OMIM:
603819
Synonyms:
SRA, STRAA1

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:
decreased bone mineral content, abnormal bone structure, abnormal optic disk morphology, decreased prepulse inhibition

Subcellular localization

cilia, nucleus

References: PMID:41005307

Functional category

  • Ciliary assembly/disassembly
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

SRA1 has localized in cilia.