SRA1
steroid receptor RNA activator 1
- Ensembl:
- ENSG00000213523
- UniProt:
- Q9HD15
- OMIM:
- 603819
- Synonyms:
- SRA, STRAA1
Cilia effects upon perturbation of SRA1
Ciliogenesis screen results (4 screens)
- Kim2016: Not Reported
- Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
- Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
Phenotypes
- Mouse phenotype:
- decreased bone mineral content, abnormal bone structure, abnormal optic disk morphology, decreased prepulse inhibition
- Mouse ciliopathy phenotype:
- abnormal cranium morphology, abnormal uterus morphology, small kidney
Subcellular localization
cilia, nucleus
Functional category
- Ciliary assembly/disassembly
- Signaling (Hedgehog, GPCRs, ion channels)
Function
SRA1 has localized in cilia.