ST3GAL5

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

Ensembl:
ENSG00000115525
UniProt:
Q9UNP4
OMIM:
604402
Synonyms:
SIAT9, SIATGM3S, ST3GALV

Cilia effects upon perturbation of ST3GAL5

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-6.16) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Elliott et al. 2025 (CRISPRa) [CRISPRa]: Disassembly Trigger (casTLE Effect=-2.72) PMID:41160700

Subcellular localization

basal body

Functional category

  • Ciliary assembly/disassembly

Function

Cells subjected to trichoplein knockdown displayed decreased levels of phosphorylated Akt in the cytoplasm, and around the ciliary base in particular (33691104).