STK16

serine/threonine kinase 16

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000115661
UniProt:
O75716
OMIM:
604719
Synonyms:
MPSK, PKL12

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-2.84) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:
increased hemoglobin content, abnormal spil cord morphology, increased mean corpuscular hemoglobin concentration

Subcellular localization

basal body, cilia, ciliary tip

References: PMID:41005307

Functional category

  • Ciliary assembly/disassembly

Function

STK16 has localized in basal body, cilia.