STK16
serine/threonine kinase 16
- Ensembl:
- ENSG00000115661
- UniProt:
- O75716
- OMIM:
- 604719
- Synonyms:
- MPSK, PKL12
Cilia effects upon perturbation of STK16
Ciliogenesis screen results (4 screens)
- Kim2016: Not Reported
- Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-2.84) PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
- Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
Phenotypes
- Mouse phenotype:
- increased hemoglobin content, abnormal spil cord morphology, increased mean corpuscular hemoglobin concentration
- Mouse ciliopathy phenotype:
- increased heart weight
Subcellular localization
basal body, cilia
Functional category
- Ciliary assembly/disassembly
Function
STK16 has localized in basal body, cilia.