STK33
serine/threonine kinase 33
Tier: Gold Standard Ciliary Genes
- Ensembl:
- ENSG00000130413
- UniProt:
- Q9BYT3
- OMIM:
- 607670
Ciliogenesis screen results (2 screens)
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
- Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
Phenotypes
- Mouse phenotype:
- increased fasting circulating glucose level, thrombocytopenia
Subcellular localization
flagella
References: PMID:41005307
Functional category
- Reproduction & sperm
Function
Stk33 is essential for spermiogenesis and male fertility, and Stk33 influences manchette function and sperm tail formation(29155043).