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synoviolin 1

Synonyms:: DER3, HRD1

Subcellular localization

Ciliary associated gene, Nucleoplasm, Endoplasmic reticulum, Plasma membrane

Function

SYVN1 ubiquitinates KIF11 at K953 and antagonizes KIF11 UFMylation, thereby regulating KIF11 stability and contributing to photoreceptor cilium integrity and retinal homeostasis(38666385).

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