SYVN1

synoviolin 1

Tier: Cilia-Associated Genes

Ensembl:: ENSG00000162298
OMIM:: 608046
Synonyms:: DER3, HRD1

Subcellular localization

Nucleoplasm, Endoplasmic reticulum, Plasma membrane

Function

SYVN1 ubiquitinates KIF11 at K953 and antagonizes KIF11 UFMylation, thereby regulating KIF11 stability and contributing to photoreceptor cilium integrity and retinal homeostasis(38666385).

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