TAF8

TATA-box binding protein associated factor 8

Ensembl:
ENSG00000137413
UniProt:
Q7Z7C8
OMIM:
609514
Synonyms:
FLJ32821, TAF(II)43, TBN

Cilia effects upon perturbation of TAF8

Ciliogenesis screen results (2 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: Increased Signaling (Negative Regulator) PMID:29459680

Phenotypes

Mouse phenotype:
embryonic lethality prior to organogenesis, preweaning lethality, complete penetrance, embryonic lethality prior to tooth bud stage

Subcellular localization

flagella, nucleus

Functional category

  • T cell biology

Function

TAF8 has localized in flagella.