TAS2R46

taste 2 receptor member 46

Ensembl:
ENSG00000278111, ENSG00000226761, ENSG00000262525
UniProt:
P59540
OMIM:
612774
Synonyms:
T2R54

Cilia effects upon perturbation of TAS2R46

Ciliogenesis screen results (2 screens)

  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Ciliopathy associations

  • Nonsyndromic Tetralogy of Fallot

Subcellular localization

cilia

Functional category

  • Ciliary assembly/disassembly
  • Signaling (Hedgehog, GPCRs, ion channels)
  • Ciliary membrane

Function

T2Rs , T2R4, T2R43, T2R38 and T2R46 , localize along the motile cilia of airway epithelia(19628819).