TBC1D21

TBC1 domain family member 21

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000167139
UniProt:
Q8IYX1
OMIM:
620387
Synonyms:
MGC34741, MGCRABGAP

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

flagella

References: PMID:25613900

Functional category

  • Ciliary assembly/disassembly
  • Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
  • Actin & cytoskeleton regulation
  • Reproduction & sperm
  • Cell migration & adhesion

Function

TBC1D21 has localized in flagella.