TBC1D31

TBC1 domain family member 31

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000156787
UniProt:: Q96DN5
Synonyms:: GM85, MGC21654, WDR67

Cilia effects upon perturbation of TBC1D31

Cilia number / % ciliated:: Decreased cilia number
Loss-of-function effect:: Shorter cilia

Ciliogenesis screen results (2 screens)

Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Pusapati et al. 2018 (CRISPR) [CRISPR]: Negative Regulator (Hh signaling, pos_rank=118, lfc=0.51) PMID:30270045

Subcellular localization

centrosome, cilia, basal body

References: PMID:41005307

Functional category

Ciliary assembly/disassembly

Function

TBC1D31 has localized in cilia.

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