TCEA2

transcription elongation factor A2

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000171703
UniProt:
Q15560
OMIM:
604784
Synonyms:
TFIIS

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-2.30) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:
decreased leukocyte cell number, abnormal coat/hair pigmentation, hyperactivity

Subcellular localization

centrosome, cilia, nucleus, basal body

References: PMID:41005307

Functional category

  • Ciliary assembly/disassembly
  • Transcription regulation

Function

TCEA2 has localized in cilia.