TCEA2
transcription elongation factor A2
- Ensembl:
- ENSG00000171703
- UniProt:
- Q15560
- OMIM:
- 604784
- Synonyms:
- TFIIS
Cilia effects upon perturbation of TCEA2
Ciliogenesis screen results (4 screens)
- Kim2016: Not Reported
- Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-2.30) PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
- Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
Phenotypes
- Mouse phenotype:
- decreased leukocyte cell number, abnormal coat/hair pigmentation, hyperactivity
- Mouse ciliopathy phenotype:
- decreased circulating calcium level, prolonged qrs complex duration
Subcellular localization
centrosome, cilia, nucleus
Functional category
- Ciliary assembly/disassembly
- Transcription regulation
Function
TCEA2 has localized in cilia.