TEKT4

tektin 4

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000163060
UniProt:
Q8WW24
Synonyms:
MGC27019

Ciliogenesis screen results (2 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-3.53) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Subcellular localization

cilia, flagella, nucleus

References: PMID:41410385, PMID:22774605, PMID:16596631

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation
  • Reproduction & sperm
  • Cell migration & adhesion

Function

Axonemal protein required for flagella motility in mouse sperm. Expression reduced in i sthenozoospermic men (22774605, 16596631)