TLR6

toll like receptor 6

Ensembl:
ENSG00000174130
UniProt:
Q9Y2C9
OMIM:
605403
Synonyms:
CD286

Cilia effects upon perturbation of TLR6

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-2.38) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

cilia associated gene

Functional category

  • Ciliary assembly/disassembly
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

LR6 is an essential partner of TLR2 in this process. TLR6 alone was required to set the number of cortical neurons under healthy conditions(PMID: 37052506).