TMEM145
transmembrane protein 145
Tier: Gold Standard Ciliary Genes
- Ensembl:
- ENSG00000167619
- UniProt:
- Q8NBT3
- Synonyms:
- FLJ90805
Cilia effects upon perturbation of TMEM145
- Cilia number / % ciliated:
- No effect
- Loss-of-function effect:
- No effect
- Overexpression effect:
- No effect
Ciliogenesis screen results (2 screens)
- Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Phenotypes
- Mouse phenotype:
- decreased startle reflex, decreased prepulse inhibition
Subcellular localization
cilia, lysosomes
References: PMID:38989623
Functional category
- Ciliary assembly/disassembly
Function
TMEM145 are localized to the cilia of sensory neurons in the head (amphid) and tail (phasmid) of C. elegans (38989623).