TMEM80

transmembrane protein 80

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000177042
UniProt:
Q96HE8
OMIM:
620248
Synonyms:
FLJ38216

Ciliogenesis screen results (2 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-2.66) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Subcellular localization

transition zone

References: PMID:26982032

Functional category

  • Ciliary assembly/disassembly
  • Transition zone

Function

Repertoire of MKS module-associated proteins—mammalian Tmem80—and suggest an MKS-5 and CEP-290-dependent assembly pathway for building a functional TZ(PMID: 26982032).