TNR

tenascin R

Ensembl:: ENSG00000116147
OMIM:: 601995

Cilia effects upon perturbation of TNR

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-2.20) PMID:26167766
Kim et al. 2010 (siRNA) [siRNA]: Shorter Cilia (Area per Cilia z=-2.47) PMID:20393562

Phenotypes

Mouse phenotype:: abnormal circulating phosphate level; abnormal locomotor activation; increased spleen weight

Ciliopathy associations

Juvenile Myoclonic Epilepsy

Subcellular localization

Ciliary associated gene

Functional category

Motile cilium & axoneme

Function

Mutations in TNR cause Juvenile Myoclonic Epilepsy (PMID: 39616287).

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