TOM1

target of myb1 membrane trafficking protein

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000100284
UniProt:
O60784
OMIM:
604700

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

cilia, cytosol, endosome

References: PMID:37019113

Functional category

  • Ciliary assembly/disassembly
  • Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
  • Protein processing & maturation

Function

Chlamydomonas TOM1 is required for the removal of ubiquiti ted proteins from cilia(37019113).