TPPP2

tubulin polymerization promoting protein family member 2

Ensembl:
ENSG00000179636
UniProt:
P59282
OMIM:
616956
Synonyms:
C14ORF8, CT152, P18, P25BETA

Cilia effects upon perturbation of TPPP2

Ciliogenesis screen results (2 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Subcellular localization

cilia

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation
  • T cell biology
  • Reproduction & sperm
  • Cell migration & adhesion

Function

IFT transport and sig lling defects after knockdown, ciliary frequency not affected. Candidate cilia gene.