TRHR
thyrotropin releasing hormone receptor
- Ensembl:
- ENSG00000174417
- UniProt:
- P34981
- OMIM:
- 188545
Cilia effects upon perturbation of TRHR
Ciliogenesis screen results (3 screens)
- Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-6.46) PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
- Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
Subcellular localization
cilia associated gene
Functional category
- Ciliary assembly/disassembly
- Signaling (Hedgehog, GPCRs, ion channels)
Function
Directio lly selective RGCs that are CART positive or Trhr positive localize either Arl13b or AC3, respectively, in cilia ( 35434813).
Model organism evidence
Mus musculus (1 reference)
Distribution of prototypical primary cilia markers in subtypes of retinal ganglion cells.
PMIDs: 35434813