TRHR

thyrotropin releasing hormone receptor

Tier: Cilia-Associated Genes

Ensembl:
ENSG00000174417
UniProt:
P34981
OMIM:
188545

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-6.46) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

No ciliary localization reported (cilia-associated gene).

References: PMID:35434813

Functional category

  • Ciliary assembly/disassembly
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

Directionally selective RGCs that are CART positive or Trhr positive localize either Arl13b or AC3, respectively, in cilia ( 35434813).