TRIM34

tripartite motif containing 34

Ensembl:: ENSG00000258659
UniProt:: Q9BYJ4
OMIM:: 605684
Synonyms:: RNF21

Cilia effects upon perturbation of TRIM34

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-6.76) PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Subcellular localization

cilia

Functional category

Ciliary assembly/disassembly
T cell biology
Viral interactions
Transcription regulation

Function

TRIM proteins localize to the centrosome and regulate cilia formation through condensation, highlighting the potential of TRIM condensates as key modulators in centrosome and cilia biology(PMID: 40450692).

Note: Additional interactive sections (perturbation matrix visualization, phylogenetic conservation strip, protein complex network, STRING interactions) require JavaScript. Browse CiliaHub for the full experience.