TRPV5

transient receptor potential cation channel subfamily V member 5

Tier: Cilia-Associated Genes

Ensembl:
ENSG00000274348
UniProt:
Q9NQA5
OMIM:
606679
Synonyms:
CAT2, ECAC1

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-3.11) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

No ciliary localization reported (cilia-associated gene).

References: PMID:15483124

Functional category

  • Ciliary assembly/disassembly
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

TRPV5/6 aren't ciliary, but may work alongside cilia-regulated systems to maintain calcium balance( 15483124).