TSGA10

testis specific 10

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000135951
UniProt:: Q9BZW7
OMIM:: 607166
Synonyms:: CEP4L, CT79

Ciliogenesis screen results (3 screens)

Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Ciliopathy associations

Male Infertility

References: PMID:37670815

Subcellular localization

basal body, nucleus, transition zone

References: PMID:16643851

Functional category

Ciliary assembly/disassembly
Reproduction & sperm
Transition zone

Function

Role in spermatogenesis. Possible role in the structure of primary cilium, as it was found to colocalise with gamma- tubulin in COS-1 cells (16643851).

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