TTC36

tetratricopeptide repeat domain 36

Ensembl:: ENSG00000172425
UniProt:: A6NLP5
OMIM:: 620701
Synonyms:: HBP21

Cilia effects upon perturbation of TTC36

Cilia number / % ciliated:: Decreased cilia number
Loss-of-function effect:: Shorter cilia

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-3.02) PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Subcellular localization

cilia

Functional category

Ciliary assembly/disassembly

Function

TTC36 mainly interacted with IFT-A complex(25860617).

Note: Additional interactive sections (perturbation matrix visualization, phylogenetic conservation strip, protein complex network, STRING interactions) require JavaScript. Browse CiliaHub for the full experience.