TUBA3E
tubulin alpha 3e
- Ensembl:
- ENSG00000292120, ENSG00000152086
- UniProt:
- Q6PEY2
- OMIM:
- 619918
Cilia effects upon perturbation of TUBA3E
Ciliogenesis screen results (1 screen)
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Subcellular localization
cilia, nucleus
Functional category
- Ciliary assembly/disassembly
- Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
- Actin & cytoskeleton regulation
- Viral interactions
- Protein processing & maturation
- Signaling (Hedgehog, GPCRs, ion channels)
Function
TUBA3E has localized in primary cilia.
Model organism evidence
C. elegans (1 reference)
The major alpha-tubulin K40 acetyltransferase alphaTAT1 promotes rapid ciliogenesis and efficient mechanosensation.
PMIDs: 21068373