TUBB8

tubulin beta 8 class VIII

Ensembl:: ENSG00000261456
UniProt:: Q3ZCM7
OMIM:: 616768
Synonyms:: BA631M21.2

Cilia effects upon perturbation of TUBB8

Phenotypes

Human ciliopathy phenotype:: Female infertility due to fertilization defect

Subcellular localization

basal body, cilia

Functional category

Ciliary assembly/disassembly
Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
Actin & cytoskeleton regulation
Reproduction & sperm
Viral interactions
Protein processing & maturation
Signaling (Hedgehog, GPCRs, ion channels)

Function

TUBB8 has localized in basal body.

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