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Subcellular localization

Ciliary associated gene, Nucleoplasm, Cytosol

Functional category

• Metabolism
• Cilia–cytoskeleton/adhesion links

Function

Impairment of POC1B, TUBE1 or TUBD1, which disturbs integrity of centriole microtubules, also prevents centriole-to-centrosome conversion. We propose that the CEP295, CEP44, POC1B, TUBE1 and TUBD1 centriole biogenesis pathway that functions in the centriole lumen and on the cytoplasmic side is essential for the centriole-to-centrosome conversion(32060285).