UNC13D

unc-13 homolog D

Ensembl:
ENSG00000092929
UniProt:
Q70J99
OMIM:
608897
Synonyms:
MUNC13-4

Cilia effects upon perturbation of UNC13D

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

cilia associated gene

Functional category

  • Ciliary assembly/disassembly
  • Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
  • Actin & cytoskeleton regulation
  • T cell biology
  • Cell migration & adhesion

Function

SLC38A4 exhibited an opposite regulatory trend in ARL3T31A and ARL3T31A/C118F groups, while IQUB, UNC13D, RAB3IP, and GRIP1 were specifically downregulated in the ARL3T31A/C118F group ( 38457249).