UXT

ubiquitously expressed prefoldin like chaperone

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000126756
UniProt:
Q9UBK9
OMIM:
300234
Synonyms:
ART-27, SKP2, STAP1

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-4.83) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

basal body, centrosome, cytosol, nucleus, transition zone

References: PMID:41005307

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation
  • Protein processing & maturation
  • Transition zone

Function

UXT has localized in basal body, transition zone.