WRAP53

WD repeat containing antisense to TP53

Ensembl:
ENSG00000141499
UniProt:
Q9BUR4
OMIM:
612661
Synonyms:
WDR79, TCAB1, FLJ10385

Cilia effects upon perturbation of WRAP53

Ciliogenesis screen results (5 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: Positive Regulator (Hh signaling, casTLE effect=-2.37) PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: Joubert Candidate / Ciliogenesis Defect (robust z=-2.07, ciliated=21.8%) PMID:26595381
  • Kim et al. 2010 (siRNA) [siRNA]: Longer Cilia (Area per Cilia z=2.83) PMID:20393562

Subcellular localization

cilia, cytosol, nuclear bodies, nucleoplasm

Function

WRAP53 has located to motile cilia.