YBX2

Y-box binding protein 2

Ensembl:
ENSG00000288504, ENSG00000006047
UniProt:
Q9Y2T7
OMIM:
611447
Synonyms:
CONTRIN, CSDA3, MSY2

Cilia effects upon perturbation of YBX2

Ciliogenesis screen results (4 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
  • Elliott et al. 2025 (CRISPRa) [CRISPRa]: Disassembly Trigger (casTLE Effect=-4.84) PMID:41160700

Subcellular localization

cilia, nucleus

Functional category

  • Ciliary assembly/disassembly
  • Reproduction & sperm

Function

Ckb and Ybx2 are involved in the interaction with Ribc2 and are necessary for the ciliary beating of multi-cilia(36508087).