YIF1B

Yip1 interacting factor homolog B, membrane trafficking protein

Ensembl:
ENSG00000167645
UniProt:
Q5BJH7
OMIM:
619109
Synonyms:
FINGER8

Cilia effects upon perturbation of YIF1B

Loss-of-function effect:
No effect

Ciliogenesis screen results (2 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Subcellular localization

cilia associated gene, lysosomes

Functional category

  • Ciliary assembly/disassembly
  • Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
  • Actin & cytoskeleton regulation

Function

YIF1B mutations cause a post- tal neurodevelopmental syndrome associated with Golgi and primary cilium alterations ( 33103737)