ZC4H2

zinc finger C4H2-type containing

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000126970
UniProt:
Q9NQZ6
OMIM:
300897
Synonyms:
HCA127, KIAA1166, MCS, MRXS4, WWS

Ciliogenesis screen results (2 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Phenotypes

Human ciliopathy phenotype:
Intellectual disability-developmental delay-contractures syndrome

Subcellular localization

cilia, nucleus, basal body

References: PMID:41005307

Functional category

  • Ciliary assembly/disassembly
  • Transcription regulation

Function

ZC4H2 has localized in cilia (PMID 41005307).