ZNF408

zinc finger protein 408

Ensembl:
ENSG00000175213
UniProt:
Q9H9D4
OMIM:
616454
Synonyms:
ZNF408, ZNF408, ENSG00000175213, EVR6, RP72

Cilia effects upon perturbation of ZNF408

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Human ciliopathy phenotype:
retinitis pigmentosa

Subcellular localization

centriolar satellites, cytosol

Function

Mutations in the ZNF408 gene cause Retinitis Pigmentosa(PMID: 25882705).